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Sorafenib (Nexavar)
Cat. No.: REK7-K77
Type: Inhibitor
Type: Inhibitor
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| Key Details | |
|---|---|
| Target | Kinases |
| CAS No. | 475207-59-1 |
| Specification | Powder |
| Formula | C₂₁H₁₆ClF₃N₄O₃·C₇H₈O₃S |
| M.W. | 637.03 |
| Purity | >98% |
| Application | Sorafenib (Nexavar) is a novel, small molecular inhibitor of several tyrosine protein kinases (VEGFR and PDGFR) and RAF/MEK/ERK cascade inhibitor with an IC50 of 6, 22, 38 nM for Raf-1, wt BRAF and V599E mutant BRAF. |
| Storage/Stability | at -20°C for 2 years as powder |
| Shipping | Ice Pack |
